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Index > Protein center > Dio2(Gene name) > Mouse
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  • Dio2 (Gene name),
  • Type II iodothyronine deiodinase (Protein name ),  IOD2_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    Dio2;
    Protein name:
    Type II iodothyronine deiodinase;
    Alternative:
    DIOII;5DII;Type-II 5'-deiodinase;Type 2 DI;
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Interacts with USP20 and USP33. Interacts with MARCH6.
    Function:
    Responsible for the deiodination of T4 (3,5,3',5'-tetraiodothyronine) into T3 (3,5,3'-triiodothyronine). Essential for providing the brain with appropriate levels of T3 during the critical period of development.
    Subcellular Location:
    Membrane Single-pass membrane protein
    Protein Attributes:
    Sequence length:
    266
    Sequence:
    50:
    MGLLSVDLLI | TLQILPVFFS | NCLFLALYDS | VILLKHVALL | LSRSKSTRGE | 
    100:
    WRRMLTSEGL | RCVWNSFLLD | AYKQVKLGED | APNSSVVHVS | NPESGNNYAS | 
    150:
    EKTADGAECH | LLDFASAERP | LVVNFGSATU | PPFTRQLPAF | RQLVEEFSSV | 
    200:
    ADFLLVYIDE | AHPSDGWAVP | GDSSLSFEVK | KHRNQEDRCA | AAHQLLERFS | 
    250:
    LPPQCQVVAD | RMDNNANVAY | GVAFERVCIV | QRRKIAYLGG | KGPFSYNLQE | 
    266:
    VRSWLEKNFS | KRUILD
    3D Structure:
    N/A
    Predicted Eptitope:
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    EIAab Sequence  Vaild Sequence:
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    Related Databases
    String:
    KEGG:
    Pfam:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse Type II iodothyronine deiodinase
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    E0578h
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    ELISA Kit for Mouse Type II iodothyronine deiodinase
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    E0578r
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    ELISA Kit for Mouse Type II iodothyronine deiodinase
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    E0578m
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    ELISA Kit for Mouse Type II iodothyronine deiodinase
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    E0578b
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    ELISA Kit for Mouse Type II iodothyronine deiodinase
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    E0578c
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    ELISA Kit for Mouse Type II iodothyronine deiodinase
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    E0578p
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    Packing:
    96T
    CLIA Kit for Mouse Type II iodothyronine deiodinase
    Cat.:
    U0578c
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    96T
    CLIA Kit for Mouse Type II iodothyronine deiodinase
    Cat.:
    U0578b
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Mouse Type II iodothyronine deiodinase
    Cat.:
    U0578m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse Type II iodothyronine deiodinase
    Cat.:
    U0578h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse Type II iodothyronine deiodinase
    Cat.:
    U0578r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse Type II iodothyronine deiodinase
    Cat.:
    U0578p
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    Please sign in first.
    MSDS:
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    Packing:
    96T
    Polyclonal Antibody for Mouse Type II iodothyronine deiodinase
    Cat.:
    P0578Rb-h
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse Type II iodothyronine deiodinase
    Cat.:
    P0578Rb-r
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse Type II iodothyronine deiodinase
    Cat.:
    P0578Rb-m
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse Type II iodothyronine deiodinase
    Polyclonal Antibody for Mouse Type II iodothyronine deiodinase
    Polyclonal Antibody for Mouse Type II iodothyronine deiodinase
    Monoclonal Antibody for Mouse Type II iodothyronine deiodinase
    Monoclonal Antibody for Mouse Type II iodothyronine deiodinase
    Monoclonal Antibody for Mouse Type II iodothyronine deiodinase
    Monoclonal Antibody for Mouse Type II iodothyronine deiodinase
    Monoclonal Antibody for Mouse Type II iodothyronine deiodinase
    Monoclonal Antibody for Mouse Type II iodothyronine deiodinase
    Protein for Mouse Type II iodothyronine deiodinase
    Protein for Mouse Type II iodothyronine deiodinase
    Protein for Mouse Type II iodothyronine deiodinase
    Protein for Mouse Type II iodothyronine deiodinase
    Protein for Mouse Type II iodothyronine deiodinase
    Protein for Mouse Type II iodothyronine deiodinase

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    Linearity
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    References
    1. 1.
      "Cloning of a 5.8 kb cDNA for a mouse type 2 deiodinase."
      Davey J.C. , Schneider M.J. , Becker K.B. , Galton V.A.
      Endocrinology140:1022-1025(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      tissue: Brain.
    2. 2.
      "Biochemical and molecular biological evidence for the presence of type II iodothyronine deiodinase in mouse mammary gland."
      Song S. , Sorimachi K. , Adachi K. , Oka T.
      Mol. Cell. Endocrinol.160:173-181(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];BIOPHYSICOCHEMICAL PROPERTIES;TISSUE SPECIFICITY
      strain: C3H/HeN.
      tissue: Brain.
    3. 3.
      "Type 2 iodothyronine deiodinase expression in the cochlea before the onset of hearing."
      Campos-Barros A. , Amma L.L. , Faris J.S. , Shailam R. , Kelley M.W. , Forrest D.
      Proc. Natl. Acad. Sci. U.S.A.97:1287-1292(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      tissue: Cochlea.
    4. 4.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Brain.
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